Murray Gell-Mann, SFI Distinguished Professor and winner of the 1969 Nobel Prize in physics was one of the originators of the Santa Fe Institute, an interdisciplinary research center in New Mexico that is celebrating its 25th anniversary this year. Gell-Mann recently addressed a group of about 150 high school students gathered at the Institute for Advanced Study in Princeton, N.J., for Adventures of the Mind, a biennial summit for academically outstanding 15- to 18-year-olds. Gell-Mann described the origins of and philosophy behind the Santa Fe Institute’s approach to science.